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Silmitasertib is a potent and selective inhibitor of CK2 (casein kinase 2).
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Smoothened Agonist (SAG) HCl is a cell-permeable?Smoothened (Smo) agonist.
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GANT61 is an inhibitor for GLI1 as well as GLI2-induced transcription.
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Purmorphamine, which directly binds and activates?Smoothened, blocks BODIPY-cyclopamine binding to Smo.
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Cyclopamine is a specific Hedgehog (Hh) signaling pathway antagonist of Smoothened (Smo).
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Vismodegib(维莫德吉) is an orally bioavailable small molecule with potential antineoplastic activity.
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IQ-1 enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation, Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells and prevents PP2A/Nkd interaction.
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SKL2001 is a novel agonist of the Wnt/β-catenin pathway.
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Wnt agonist 1 HCl is the hydrochloride salt of Wnt agonist 1, which is a cell permeable Wnt signaling pathway activator.
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KY02111 promotes differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, may act downstream of APC and GSK3β.
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