产品名称

Xanthine Oxidase from bovine milk

一般描述

Xanthine oxidase is a molybdenum-containing enzyme that is found in the cytosol, and may be strongly inhibited by flavonoids.

别 称

XOD, Xanthine:oxygen oxidoreductase

含 量

≥0.1 units/mg protein

CAS  NO.

9002-17-9

MDL  number

MFCD00082145

适用范围

生物试剂

l  理化信息

外 观

硫酸铵悬浮液

l  生物学信息

生物活性/药理作用

Although xanthine oxidase is found widely distributed in multiple tissues, it is highly expressed in endothelial and epithelial cells. Its was also increased in infected tissues where it was shown to have an anti-microbial effect due to its ability to generate reactive oxygen species.Xanthine oxidase is a molybdenum-containing enzyme that is found in the cytosol, and may be strongly inhibited by flavonoids. It plays a vital role in the bolism of some drugs, as well as purines and pyrimidines. It is also known to be a biological source of reactive oxygen species.

有效单位定义

One unit will convert 1.0 μmole of xanthine to uric acid per min at pH 7.5 at 25 °C. Approx. 50% of the activity is obtained with hypoxanthine as substrate.

l  存储

存储温度

2-8°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov