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  • DNA Ligase from T4-infected Escherichia coli
    TL0023

    Thalidomide(沙利度胺) is a piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.

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  • DNA Ligase from T4-infected Escherichia coli
    TL0732

    P005091 is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7).

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  • DNA Ligase from T4-infected Escherichia coli
    TL0760

    PRT 4165 is a Bmi1/Ring1A inhibitor, also inhibits PRC1-mediated H2A ubiquitylation in vivo and in vitro.

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  • DNA Ligase from T4-infected Escherichia coli
    TL0798

    DBeQ is a selective, potent, reversible, and ATP-competitive p97 inhibitor.

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  • DNA Ligase from T4-infected Escherichia coli
    TS0373
    MG132 is a potent cell-permeable proteasome and calpain inhibitor.
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  • DNA Ligase from T4-infected Escherichia coli
    TS0375
    BAY 11-7082 is a NF-κB inhibitor.
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  • DNA Ligase from T4-infected Escherichia coli
    TS2258
    b-AP15 is a deubiquitinases inhibitor for 19S proteasomes activity of Ub-AMC cleavage with IC50 of 2.1 μM.
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  • DNA Ligase from T4-infected Escherichia coli
    TS2259
    MNS is a tyrosine kinase inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.
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