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  • DNA Ligase from T4-infected Escherichia coli
    TL0731

    XAV-939 selectively inhibits Wnt/β-catenin-mediated tranion through tankyrase1/2 inhibition, regulates axin levels and does not affect CRE, NF-κB or TGF-β.

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  • DNA Ligase from T4-infected Escherichia coli
    TL0795

    CIL56(CA3) has potent inhibitory effects on YAP1/Tead tranional activity and primarily targets YAP1 high and therapy-resistant esophageal adenocarcinoma cells endowed with CSC properties.

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  • DNA Ligase from T4-infected Escherichia coli
    TL0808

    KY02111 promotes differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, may act downstream of APC and GSK3β.

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  • DNA Ligase from T4-infected Escherichia coli
    TL0819

    Wnt agonist 1 HCl is the hydrochloride salt of Wnt agonist 1, which is a cell permeable Wnt signaling pathway activator.

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  • DNA Ligase from T4-infected Escherichia coli
    TL0836

    SKL2001 is a novel agonist of the Wnt/β-catenin pathway.

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  • DNA Ligase from T4-infected Escherichia coli
    TL0838

    IQ-1 enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation, Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells and prevents PP2A/Nkd interaction.

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  • DNA Ligase from T4-infected Escherichia coli
    TS0367

    Vismodegib(维莫德吉) is an orally bioavailable small molecule with potential antineoplastic activity.

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  • DNA Ligase from T4-infected Escherichia coli
    TS0368

    Cyclopamine is a specific Hedgehog (Hh) signaling pathway antagonist of Smoothened (Smo).

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