Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold).
Panobinostat(帕比司他), a cinnamic hydroxamic acid analogue, is a novel broad-spectrum inhibitor of HDAC with potential antineoplastic activity.
Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.
Quercetin(槲皮素) is a polyphenolic flavonoid with potential chemopreventive activity.
Apabetalone (RVX-208), a potent BET bromodomain inhibitor, has been investigated for the treatment of Diabetes, Atherosclerosis, and Coronary Artery Disease.
Curcumin(姜黄素) is a natural component of the rhizome of turmeric. Its biological effects range from antioxidant, anti-inflammatory to inhibition of angiogenesis and is also shown to possess specific antitumoral activity.
Decitabine(地西他滨) is a cytidine antimetabolite analogue with potential antineoplastic activity.
Divalproex Sodium(丙戊酸半钠) is a stable coordination compound comprised of sodium valproate and valproic acid with anticonvulsant and antiepileptic activities.