备注：
库存充足，如需更大包装，请联系销售人员，大包装有极大的折扣优惠！
详细介绍
l 基本信息 |
产品名称 | 贝利司他(Belinostat) |
一般描述 | Belinostat
is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with
antineoplastic activity. |
别 称 | N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide;
PXD-101;贝林司他;
NSC726630; PX-105684 |
纯 度 | ≥98%(HPLC) | CAS NO. | 414864-00-9 |
分子式 | C15H14N2O4S | 分子量 | 318.347 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 浅粉色固体 |
溶解性(25℃) | DMSO | ≥50mg/mL |
乙醇 | Insoluble |
水 | Insoluble |
l 生物学信息 |
生物活性/药理作用 | Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing
apoptosis, promoting cellular differentiation, and inhibiting angiogenesis.
This agent may sensitize drug-resistant tumor cells to other antineoplastic
agents, possibly through a mechanism involving the down-regulation of thymidylate synthase. |
l 包装与存储 |
包 装 | 10mg; 50mg; 250mg |
存储温度 | -20℃ |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
