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  • DNA Ligase from T4-infected Escherichia coli
    TL0074

    FLLL32 is a potent JAK2/STAT3 inhibitor with IC50 of <5 μM.

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  • DNA Ligase from T4-infected Escherichia coli
    TL0139

    HO-3867, an analog of curcumin, is a selective STAT3 inhibitor.

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  • DNA Ligase from T4-infected Escherichia coli
    TL0227

    Artesunate(青蒿琥酯) is a water-soluble, semi-synthetic derivative of the sesquiterpine lactone artemisinin with anti-malarial, anti-shistosomiasis, antiviral, and potential anti-neoplastic activities.

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  • DNA Ligase from T4-infected Escherichia coli
    TL0363

    Niclosamide(氯硝柳胺) is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity.

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  • DNA Ligase from T4-infected Escherichia coli
    TL0733

    SMI-4a is a potent inhibitor of Pim1, modestly potent to Pim-2, does not significantly inhibit any other serine/threonine- or tyrosine-kinases.

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  • DNA Ligase from T4-infected Escherichia coli
    TL0820

    SGI-1776 is a novel ATP competitive inhibitor of Pim1.

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  • DNA Ligase from T4-infected Escherichia coli
    TS0277

    S3I-201 shows potent inhibition of STAT3 DNA-binding activity with IC50 of 86 μM in cell-free assays, and low activity towards STAT1 and STAT5.

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  • DNA Ligase from T4-infected Escherichia coli
    TS0278

    Stattic, the first nonpeptidic small molecule, has a role as an antineoplastic agent, a STAT3 inhibitor and a radiosensitizing agent.

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