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  • DNA Ligase from T4-infected Escherichia coli
    TS3608
    OSS_128167 is a specific SIRT6 inhibitor with IC50 values of 89, 1578 and 751 μM for SIRT6, SIRT1 and SIRT2, respectively.
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  • DNA Ligase from T4-infected Escherichia coli
    TS3618
    ACY-738 inhibits HDAC6 with low nanomolar potency (IC50=1.7 nM) and a selectivity of 60- to 1500-fold over class I HDACs.
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  • DNA Ligase from T4-infected Escherichia coli
    TS3625
    GSK3326595 (EPZ015938) is an orally active, potent and selective inhibitor of protein arginine methyltransferase 5 (PRMT5) and potently inhibits tumor growth in vitro and in vivo in animal models.
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