产品名称

Xanthine Oxidase from bovine milk

一般描述

Xanthine oxidase is a molybdenum-containing enzyme that is found in the cytosol, and may be strongly inhibited by flavonoids.

别 称

XOD, Xanthine:oxygen oxidoreductase

含 量

0.4-1.0 units/mg protein

CAS  NO.

9002-17-9

MDL  number

MFCD00082145

适用范围

生物试剂

l  理化信息

外 观

冻干粉

l  生物学信息

生物活性/药理作用

The isoflavanoid genistein was shown to inhibit xanthine oxidase at concentrations between 0.1-4.0 μM and then activate xanthine oxidase at concentrations higher than 5 μM.Xanthine oxidase is a molybdenum-containing enzyme that is found in the cytosol, and may be strongly inhibited by flavonoids. It plays a vital role in the bolism of some drugs, as well as purines and pyrimidines. It is also known to be a biological source of reactive oxygen species.

样品准备说明

This enzyme is soluble in 50 mM potassium, phosphate buffer (1 mg/ml), yielding a clear solution.

有效单位定义

One unit will convert 1.0 μmole of xanthine to uric acid per min at pH 7.5 at 25 °C. Approx. 50% of the activity is obtained with hypoxanthine as substrate.

l  存储

存储温度

2-8°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov