L-Lactic Dehydrogenase from rabbit muscle
商品编号：
S0023
备注：
国外库存，货期2-4周，具体详情请联系销售人员。
详细介绍
l 基本信息 |
产品名称 | L-Lactic Dehydrogenase from rabbit muscle |
一般描述 | L-lactic dehydrogenase catalyzes the conversion of L-lactate into L-pyruvate while reducing NAD+ to NADH and H+. |
别 称 | (S)-Lactate: NAD+ oxidoreductase, L-LDH, LAD, LD, Lactate |
含 量 | 800-1,200 units/mg protein | CAS
NO. | 9001-60-9 |
MDL
number | MFCD00131466 |
适用范围 | 生物试剂 |
l 生物学信息 |
生物活性/药理作用 | Also catalyzes the oxidation of other L-2-hydroxymonocarboxylic acids. Lactic Dehydrogenase (LDH) has a total molecular weight of 140 kDa and is composed of 4 subunits which are designated M subunit (muscle) and H subunit (heart).These subunits may be mixed in any of 5 combinations (M4, M3H1, M2H2, MH3, and H4).Skeletal muscle contains LDH that is predominately M4 with some small amounts of M3H and traces of H2H2. The H and M subunits are quite similar in molecular weight, but differ substantially in amino acid composition. Rabbit muscle LDH dissociates into dimeric species (MW = ~70 kDa) in acetate-chloride at pH 5.0, the dissociation is reversible. Biochemistry, 13, 3527-3531 (1974).Oxidizes glyoxylate and lactate. Isoelectric point: 8.4-8.6 Optimal pH : 7.5 . |
有效单位定义 | One unit will reduce 1.0 μmole of pyruvate to L-lactate per min at pH 7.5 at 37 °C. |
l 包装与存储 |
存储温度 | 2-8°C |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
