产品名称

Glutathione Peroxidase from bovine erythrocytes

别 称

GSH-Px, Glutathione:hydrogen-peroxide oxido-reductase

含 量

≥300 units/mg protein

CAS  NO.

9013-66-5

分子量

mol wt 84.5 kDa

MDL  number

MFCD00131195

适用范围

生物试剂

l  理化信息

外 观

冻干粉

物理形态

Lyophilized powder containing 25% sucrose and 2.5% dithiothreitol with sodium phosphate buffer salts

l  生物学信息

生物活性/药理作用

Protects cells against oxidative damage by catalyzing the reduction of hydrogen peroxide in the presence of reducing agent glutathione. In cellular membranes it may induce lipid peroxidation through the reduction of hydrogen peroxide or polyunsaturated fatty acid hydroperoxides. Glutathione peroxidase is an enzyme which reduced lipid hydroperoxides into their corresponding alcohols. It also reduces free hydrogen peroxide in to water. In vivo it is responsible for protecting hemoglobin from oxidative breakdown.

应 用

Glutathione peroxidase from bovine erythrocytes was used as a positive control in cloning and characterization of full-length cDNAs encoding two glutathione peroxidases (GpXs) from Globodera rostochiensis. It was used for the determination of glutathione peroxidase activity in human milk.

有效单位定义

One unit will catalyze the oxidation by H²O²of 1.0 μmole of reduced glutathione to oxidized glutathione per min at  pH 7.0 at 25 °C.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov