产品名称

Kynurenine 3-Monooxygenase, Pseudomonas fluorescens (strain 17400), Recombinant

一般描述

Kynurenine 3-monooxygenase (KMO) is a flavoprotein aromatic hydroxylase (FAH) that catalyzes the hydroxylation of L-kynurenine (L-Kyn) to produce 3-hydroxykynurenine (3-OH-Kyn). This activity is central to tryptophan bolism and also to the production of nicotinamide adenine dinucleotide (NAD) in higher organisms. KMO contains flavin adenine dinucleotide (FAD) as a non-covalent, but tightly bound, co-factor at a 1:1 ratio of co-factor to protein.

别 称

KMO

浓 度

≥ 5 mg/ml

活 性

≥ 3UN/mg

适用范围

生物试剂

l  理化信息

外 观

溶液

l  生物学信息

生物活性/药理作用

Kynurenine 3-monooxygenase (KMO) is a flavoprotein aromatic hydroxylase (FAH) that catalyzes the hydroxylation of L-kynurenine (L-Kyn) to produce 3-hydroxykynurenine (3-OH-Kyn). This activity is central to tryptophan bolism and also to the production of nicotinamide adenine dinucleotide (NAD) in higher organisms. KMO contains flavin adenine dinucleotide (FAD) as a non-covalent, but tightly bound, co-factor at a1:1 ratio of co-factor to protein.

有效单位定义

One unit will oxidize L-kynurenine at 1#·mol/min at pH 7.0, 25#ºC

l  存储

存储温度

The recommended long-term storage temperature for the product is –70 °C.

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov