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Superoxide Dismutase from human erythrocytes

商品编号: S0121
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国外库存,货期2-4周,具体详情请联系销售人员。

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详细介绍

l  基本信息

产品名称

Superoxide Dismutase from human erythrocytes

别 称

SOD,Superoxide: superoxide oxidoreductase

含 量

≥2,500 units/mg protein

CAS  NO.

9054-89-1

MDL  number

MFCD00132404

适用范围

生物试剂

l  理化信息

外 观

白色至白色基本上无盐冻干粉末

l  生物学信息

生物活性/药理作用

Catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. Plays a critical role in the defense of cells against the toxic effects of oxygen radicals. Competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby SOD promotes the activity of NO. SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines, and transgenic mice.

样品准备说明

SOD is soluble in water (20 mg/ml) yielding a colorless to blue-green solution. SOD is also soluble in aqueous buffers such as 0.1 M potassium phosphate, pH 7.5.

有效单位定义

One unit will inhibit reduction of cytochrome c by 50% in a coupled system with xanthine oxidase at pH 7.8 at 25°C in a 3.0 mL reaction volume. Xanthine oxidase concentration should produce  an initial ΔA550 of 0.025 ± 0.005 per min.

l  包装与存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov