产品名称

Monoamine Oxidase B human

一般描述

Monoamine Oxidase B is a mitochondrial outermembrane flavoenzyme that is a target for antidepressant and neuroprotective drugs.

别 称

MAO-B

含 量

~2.5 mg per vial; Protein: ≥2.5mg/ml;  Activity: ≥1 units/mg protein;recombinant, expressed in baculovirus infected BTI insect cells

MDL  number

MFCD04040933

适用范围

生物试剂

l  生物学信息

生物活性/药理作用

MAO’s are proteins of the mitochondrial membrane. These enzymes are responsible for catalyzing oxidative deamination of endo- and xenobiotic amines. Substrate specificity differs for each isozyme.

应 用

Drugs that inhibit monoamine oxidase B activity are used for the treatment of various neurological disorders including depression. Monoamine Oxidase B has been used in a study to assess the effect of age in 23 different regions of the human brain. It has also been used in a study to determine the specific locations of monoamine oxidase in the human brain.

样品准备说明

It is recommended that the product be thawed rapidly in a 37°C water bath and kept on ice until use.

l  存储

存储温度

The product ships on dry ice and it is recommended to store the product at -70°C. Avoid repeated freeze-thaw cycles.

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov