产品名称

Fructosyl-Amino Acid Oxidase from Corynebacterium sp.

一般描述

Enzyme Commission (E.C.) 1.5.3.x; Fructosyl  amino acid oxidase [fructosyl-a-l-amino acid:oxygen oxidoreductase] is a flavoprotein  that catalyzes the oxidation of fructosyl amino acids to form glucosone, amino acid and hydrogen peroxide.

含 量

≥0.45 units/mg protein; recombinant, expressed in E. coli

分子量

mol wt ~88 kDa by electrophoresis

MDL  number

MFCD03456889

适用范围

生物试剂

l  理化信息

外 观

冻干粉

l  生物学信息

生物活性/药理作用

Suitable for the determination of fructosyl-L-amino acid.

Fructosamines are formed when glucose is condensed amino group of amino acids or proteins. Fructosamine oxidases (FAOX) catalyze the oxidative deglycation of low molecular weight fructosamines. Fructosyl amino acid oxidase catalyzes the oxidation of the C-N bond ing the C1 of the fructosyl moiety and the nitrogen of the amino group of fructosyl amino acids.

应 用

Fructosyl-amino acid oxidase can be used to detect the levels of glycated proteins, which are markers for diabetes mellitus.

有效单位定义

One unit will produce 1.0 μmole of hydrogen peroxide per minute at pH 8.0 at 37 °C.

l  包装与存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov