产品名称

Pyrimidine nucleoside phosphorylase

含 量

≥1300 U/mL; recombinant, expressed in E. coli

CAS  NO.

9055-35-0

适用范围

生物试剂

l  生物学信息

生物活性/药理作用

Pyrimidine nucleoside phosphorylase (PyNPase) is a glycosyltransferase that catalyzes the conversion of pyrimidine nucleoside and phosphate to a pyrimidine and α-D-ribose 1-phosphate. PyNPase plays a significant role in breast cancer angiogenesis.

应 用

Pyrimidine nucleoside phosphorylase (PyNPase) may be used as a marker to predict the malignant potential of breast cancer, especially lymph node stasis. PyNPase is used to study breast cancer, specifically its role in angiogenesis.

有效单位定义

One unit will convert 1 μmole each of thymidine and phosphate to thymine and 2-deoxyribose 1-phosphate per minute at pH 7.4 and 25°C

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov