产品名称

α-2,6-Sialyltransferase from Photobacterium damsela

别 称

β-Galactoside α-2,6-sialyltransferase, CMP-N-Acetylneuraminate:β-D-galactosyl-1,4-N-acetyl-β-D-glucosamine α-2,6-N-acetylneuraminyltransferase

含 量

≥5 units/mg protein; recombinant, expressed  in E. coli BL21

MDL  number

MFCD00132245

适用范围

生物试剂

l  理化信息

物理形态

Supplied as a lyophilized powder containing Tris-HCl and NaCl.

l  生物学信息

生物活性/药理作用

Sialyltransferase transfers Neu5Ac from CMP-Neu5Ac to the galactosyl terminus of acceptor molecules including glycoproteins, glycolipids, and oligosaccharides.

应 用

Highly active α2-6 sialyltransferase has been used to prepare high levels of disialylated fragment crystals.

样品准备说明

Reconstitute the lyophilized powder with water to ~5 mg/mL.

有效单位定义

One unit will catalyze the formation of 1 μmol Neu-5-Ac-α-2,6-LacMU from CMP-Neu-5-Ac and Lac-β−OMU per minute at 37 °C  at pH 8.0.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov