产品名称

Hck human

含 量

≥200 units; recombinant, expressed in E.coli BL21, vial of; 1-2 unit/μg protein

MDL  number

MFCD03792313

适用范围

生物试剂

l  理化信息

物理形态

Supplied as a solution in 50mM Tris HCl, pH 7.4, 1mM EDTA and 1mM DTT

l  生物学信息

生物活性/药理作用

Hck is a member of the Src tyrosine kinase family. Hck has been shown to associate with and be activated by Bcr-Abl, which is a protein-tyrosine kinase that is expressed in chronic myelogenous leukemia  .

应 用

Hck is a protein-tyrosine kinase that is expressed in hemopoietic cells. It is used in leukemia research .

有效单位定义

One unit will phosphorylate 1.0 picomole of Tyr₁₅ of the peptide substrate p_{cdc2 6-20} per minute at 30°C at pH 7.4.

l  存储

存储温度

−70°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov