产品名称

Esterase from rabbit liver

别 称

Carboxyl esterase, Carboxylic-ester hydrolase

含 量

≥75 units/mg protein

CAS  NO.

9016-18-6

MDL  number

MFCD00131030

适用范围

生物试剂

l  理化信息

外 观

冻干粉

物理形态

Lyophilized powder containing Tris buffer salts

l  生物学信息

生物活性/药理作用

Esterase is a gylcoprotein having a molecular mass of approximately 60 kDa and is mainly present in the endoplasmic reticulum of hepatocytes. The enzyme catalyzes hydrolysis of carboxylic ester to carboxylate and alcohol in the presence of water. Rabbit liver carboxylesterase catalyzes enantioselective hydrolysis of cineol derivatives.

应 用

Esterase from rabbit liver has been used in a study to investigate a toxic effect of carbamate insecticides. Esterase from rabbit liver has also been used in a study to investigate the effect of simvastatin on and activity of a lipoprotein-associated phospholipase A(2). The enzyme from Sigma has been used to study the effect of divalent l ions on the activity of esterase.

有效单位定义

One unit will hydrolyze 1.0 μmole of ethyl butyrate to butyric acid and ethanol per min at pH 8.0 at 25°C.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov