产品名称

Lipase from Rhizopus niveus

一般描述

Lipases hydrolyze ester bonds of triacylglycerols and in some conditions, catalyze the synthesis of ester bonds by transesterification. Lipase from Rhizopus niveus exists as a single polypeptide chain with a molecular mass of about 30-34kDa.

别 称

Triacylglycerol acylhydrolase, Triacylglycerol lipase

含 量

≥1.5 U/mg

CAS  NO.

9001-62-1

分子量

Mr ~83000

MDL  number

MFCD00131509

适用范围

生物试剂

l  理化信息

外 观

细粉

l  生物学信息

生物活性/药理作用

Tri-, di-, and monoglycerides are hydrolyzed (in decreasing order of rate).

Lipase from Rhizopus niveus is specifically used to produce cocoa butter substitutes.

应 用

Lipase from Rhizopus niveus has been used to determine the positional distribution of fatty acids within triacylglycerol by hydrolysis of the acyl ester age at C-1 and C-3. It  has also been used to induce intragastric lipolysis and study its effects on  felodipine (a medication) release from a hydrophilic, extended release tablet.

有效单位定义

1U corresponds to the amount of enzyme which liberates 1μmol fatty acid from a triglyceride per minute at pH7.7 and  40°C (olive oil as substrate); 300U as described above are equivalent to ~1U using triolein at pH8.0 and 40°C as substrate.

l  存储

存储温度

2-8°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov