Ribonuclease A from bovine pancreas
商品编号：
S0342
备注：
国外库存，货期2-4周，具体详情请联系销售人员。
详细介绍
l 基本信息 |
产品名称 | Ribonuclease A from bovine pancreas |
别 称 | Pancreatic Ribonuclease, RNase A,Ribonucleate 3′-pyrimidinooligonucleotidohydrolase |
含 量 | ≥60% RNase A basis (SDS-PAGE), ≥50 Kunitz units/mg protein; Type I-A | CAS
NO. | 9001-99-4 |
分子量 | mol wt ~13,700 | MDL
number | MFCD00132181 |
适用范围 | 生物试剂 |
l 理化信息 |
外 观 | 白色至灰白色粉末 |
l 生物学信息 |
生物活性/药理作用 | Ribonuclease A is an endoribonuclease that cleaves single stranded RNA after pyrimidine nucleotides. It attacks at the 3’ phosphate end. Ribonucleases do not hydrolyze DNA, because the DNA lacks
2′-OH groups essential for the formation of cyclic intermediates. RNase can also hydrolyze RNA from protein samples. RNase A can be inhibited by alkylation of His12 and His119 and activated by potassium and sodium salts. |
应 用 | Ribonuclease A is used to remove RNA from DNA plasmid preparations and protein samples. It is also used in RNA sequence analysis and protection assays. RNase has been used as a tool for computer-aided drug design . |
样品准备说明 | Salt fractionated and chromatographically purified. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
