产品名称

Ribonuclease B from bovine pancreas

别 称

RNase B

含 量

Protein: ≥80%(SDS-PAGE); ≥50 Kunitz units/mg protein

CAS  NO.

9001-99-4

MDL  number

MFCD00132184

适用范围

生物试剂

l  理化信息

外 观

白色至浅黄色粉末

l  生物学信息

生物活性/药理作用

Native RNase BS generated by subtilisin digestion of native RNase B comprising of amino acid residues 21-124 of RNase B, is sensitive to PNGase F digestion. Intramolecular N-glycans of bovine pancreatic RNase B function like chaperone. RNase B is found to be much  faster than RNase A, while RNase A is liable to aggregate during regeneration. The stimulatory effect of Asn-oligosaccharide (which corresponds to the most predominant sugar chain of RNase B) reveals that the N-glycans of RNase B facilitates the transformation of bulky intermediates into folded,compact species.

应 用

Ribonuclease B from bovine pancreas is used in the digestion of RNA during cell cycle platform analysis.

样品准备说明

Purified by affinity chromatography

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov