产品名称

Phosphodiesterase I from Crotalus adamanteus venom

别 称

5′-Exonuclease, Oligonucleate 5′-nucleotidohydrolase

含 量

≥0.01unit/mg solid; Type VI, crude dried venom

CAS  NO.

9025-82-5

MDL  number

MFCD00131883

适用范围

生物试剂

l  理化信息

外 观

固体

l  生物学信息

生物活性/药理作用

Phosphodiesterase I breaks phosphodiester bonds and catalyzes the hydrolysis of various nucleotide polyphosphates. Phosphodiesterase I is released from eucaryotic plasma membranes by phosphatidylinositol-specific phospholipase C.

应 用

Phosphodiesterase (PDE) is any enzyme that is used to breaks phosphodiester bonds. It is a membrane-bound glycoprotein that is used to catalyze the hydrolysis of various nucleotide polyphosphates. Phosphodiesterase I is used in phosphodiesterase activation assays to hydrolyze AMP. Product P3134 is from crude, dried Crotalus adamanteus venom.

有效单位定义

One unit will hydrolyze 1.0 μmole of bis(p-nitrophenyl) phosphate per min at pH8.8 at 37°C.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov