产品名称

Phosphodiesterase I from Crotalus atrox (Western Diamondback Rattlesnake)

别 称

5′-Exonuclease, Oligonucleate 5′-nucleotidohydrolase

含 量

Type IV, crude dried venom, ≥0.01 unit/mg solid

MDL  number

MFCD00131883

适用范围

生物试剂

l  理化信息

外 观

固体

l  生物学信息

生物活性/药理作用

Phosphodiesterase I breaks phosphodiester bonds and catalyzes the hydrolysis of various nucleotide polyphosphates. Phosphodiesterase I is released from eucaryotic plasma membranes by phosphatidylinositol-specific phospholipase C.

应 用

Phosphodiesterase (PDE) is any enzyme that is used to breaks phosphodiester bonds. Phosphodiesterase I, product P4506 from western diamondback rattlesnake, is used in phosphodiesterase activation assays for calmodulin. It is added to hydrolyze AMP. It is a membrane-bound glycoprotein that is used to catalyze the hydrolysis of various nucleotide polyphosphates.

有效单位定义

One unit will hydrolyze 1.0 μmole of bis(p-nitrophenyl) phosphate per min at pH8.8 at 37°C.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov