产品名称

Phospholipase D from Arachis hypogaea (peanut)

一般描述

Phospholipase D is a phospholipid hydrolyzing enzyme and an important component of receptor-mediated signal transduction responses and regulated secretion.

别 称

Lecithinase D, Phosphatidylcholine  phosphatidohydrolase

含 量

Protein: 20% - 40%; ≥60 units/mg protein; Type II

CAS  NO.

9001-87-0

MDL  number

MFCD00131897

适用范围

生物试剂

l  理化信息

外 观

白色至类白色或 黄色冻干粉末

物理形态

Partially purified, lyophilized powder containing buffer salts

l  生物学信息

生物活性/药理作用

Hydrolyzes the phosphate bonds of phospholipids and sphingomyelin to give the corresponding phosphatidic acid.

Phospholipase D is involved in conferring drought susceptibility in peanuts, which increases the risk of aflatoxin contamination.

应 用

Research has shown ADP-ribosylation factor regulation of phospholipase D is important in the release of nascent secretory vesicles from the trans-Golgi network. It has also been used in a study to investigate stimulation of Na₊-Ca₂₊ exchange activity in canine cardiac sarcolemmal vesicals.

有效单位定义

One unit will liberate 1.0 μmol of choline from L-α-phosphatidylcholine (egg yolk) per hr at pH5.6 at 30°C.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov