产品名称

Neuraminidase from Vibrio cholerae

一般描述

Calorimetry studies show that the two lectin-like domains flanking the central catalytic domain of Neuraminidase serve as the recognition and binding sites for sialic acid-containing substrates.

别 称

Acyl-neuraminyl Hydrolase, Receptor-destroying enzyme, Sialidase

含 量

Type II, 8-24units/mg protein (Lowry, using NAN-lactose)

CAS  NO.

9001-67-6

MDL  number

MFCD00131711

适用范围

生物试剂

l  理化信息

外 观

缓冲水溶液

物理形态

Solution in 50mM sodium acetate, pH5.5, containing 0.15M sodium chloride and 4mM calcium chloride, 0.2μm filtered.

l  生物学信息

应 用

Neurminidase is used as a cell-surface probe for glycoconjugate distribution and in substrate specificity studies. Neuraminidase from Vibrio cholera has been used in a study to describe a five-step purification method. It has also been used in a study to investigate modification of leukemia L1210 tumor cells.

样品准备说明

A further purification by affinity chromatography of our Type III.

有效单位定义

One unit will liberate 1.0μmole of  N-acetylneuraminic acid per min at pH5.0 at 37°C using NAN-lactose or bovine submaxillary mucin, unless otherwise specified. Prices d on units using NAN-lactose as substrate.

l  存储

存储温度

2-8°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov