产品名称

α-Mannosidase from Canavalia ensiformis (Jack bean)

一般描述

αMannosidase from Canavalia ensiformis is a tretamer composed of two subunits that each contain two components at 44 and 66 kDa.

别 称

α-D-Mannoside mannohydrolase

含 量

≥15units/mg protein (biuret)

CAS  NO.

9025-42-7

MDL  number

MFCD00130495

适用范围

生物试剂

l  理化信息

外 观

硫酸铵悬浮液

物理形态

Suspension in 3.0M (NH⁴)²SO⁴ and 0.1mM zinc acetate, pH7.5

l  生物学信息

生物活性/药理作用

α-Mannosidase is an acid hydrolase which is located in plant vacuoles and is thought to be involved with the turnover of N-ed glycoproteins.

αMannosidase has been shown to inhibit the proliferation of B-lymphocytes.

应 用

Liberates mannose from a variety of synthetic and natural α-mannosides.

α-Mannosidase can be used to liberate mannose from a variety of synthetic and natural α-mannosides. It has also been used in a study to investigate the causes of neurodegeneration in mucolipidosis II ′knock-in′ mice.

样品准备说明

This enzyme is soluble in water (1mg/ml), yielding a clear and colorless solution.

有效单位定义

One unit will hydrolyze 1.0μmole of p-nitrophenyl α-D-mannoside to p-nitrophenol and D-mannose per min at pH4.5 at 25°C.

l  存储

存储温度

2-8°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov