产品名称

β-Glucuronidase from Helix aspersa (garden snail)

含 量

Type HA-4; ≥300,000units/g solid solid; ≤7,500units/g solid sulfatase (secondary activity)

MDL  number

MFCD00130629

适用范围

生物试剂

l  理化信息

外 观

粉末

溶解性(25°C)

H²O: soluble 1.90-2.10mg/mL, clear to slightly hazy

l  生物学信息

生物活性/药理作用

β-glucuronidase (β-GIc) is an exoglycosidase that catalyzes the breakdown of complex carbohydrates. In humans it converts conjugated bilirubin into the unconjugated form, making  bilirubin suitable for reabsorption.

应 用

β-glucuronidase was used in enzymic hydrolysis of tissue homogenates for liquid chromatography-electrospray ion trap mass spectrometry (LC/MSn) analysis, to study the structures of degradation products of baicalin.

有效单位定义

One modified Fishman unit will liberate 1.0μg of phenolphthalein from phenolphthalein glucuronide per hr at 37°C at the pH5.0 (30 min assay).

One unit of sulfatase will hydrolyze 1.0μmole p-nitrocatechol sulfate per hr at pH5.0 at 37°C.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov