产品名称

Dipeptidyl Peptidase VII human

别 称

DPP7, Quiescent cell proline dipeptidase

含 量

recombinant, expressed in Sf9 cells; ≥1,500units/μg protein

适用范围

生物试剂

l  理化信息

物理形态

Supplied as a solution in 25mM Tris-HCl, pH8.0,130mM NaCl, 0.05% Tween-20, 10% glycerol.

l  生物学信息

生物活性/药理作用

DPP7 is essential for maintaining lymphocytes and fibroblasts in G(0). The inhibition of DPP7 results in apoptosis, which is mediated by the induction of c-Myc and p53. DPP7 has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH.

应 用

Dipeptidyl Peptidase VII (DPP7), also known as DPP2 or quiescent cell proline dipeptidase, is a post-proline cleaving aminopeptidase that is expressed in quiescent lymphocytes. DPP7 is used to study the regulation of cell quiescence. Like DPP4, DPP7 may be useful in diabetes and vascular disease research.

有效单位定义

One unit will hydrolyze 1.0 picomole of Ala-Pro-AMC per minute at pH7.4 at 25°C

l  存储

存储温度

−70°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov