产品名称

Endoproteinase Arg-C from mouse submaxillary gland

CAS  NO.

82047-85-6

MDL  number

MFCD01324999

适用范围

生物试剂,  suitable for protein sequencing

l  理化信息

外 观

冻干粉

l  生物学信息

生物活性/药理作用

Endoproteinase Arg-C is a serine endoprotease from mouse submaxillary gland which hydrolyzes peptide bonds at the carboxyl side of arginyl residues. The enzyme has been shown to cleave Lys-Lys and Lys-Arg bonds, and all Arg-X bonds may not be hydrolyzed.

应 用

Endoproteinase Arg-C from mouse submaxillary gland has been used to study the syncytium formation in MERS-CoV (middle East respiratory syndrome coronavirus)-infected Vero cells in the presence of exogenous proteases. It has been used for the digestion of Rpl23ab (ribosomal protein L23ab)-containing fraction for LC-MS (liquid chromatography–mass spectrometry)/MS analysis.

样品准备说明

Reconstitute the lyophilized product in 1mM HCl.

有效单位定义

One unit will hydrolyze 1.0μmole of Nα-p-tosyl-L-arginine methyl ester per min at pH8.0 at 25°C.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov