产品名称

Thrombin from human plasma

一般描述

Thrombin is the final coagulation protease in regard to hemostasis, promoting both procoagulant and anticoagulant effects.

别 称

Factor Iia

含 量

≥2800 NIH units/mg protein (E1%/280,18.3)

CAS  NO.

9002-04-4

MDL  number

MFCD00082072

适用范围

生物试剂

l  理化信息

外 观

白色冻干粉

物理形态

Lyophilized from 0.02M Bis/Tris buffer, pH6.5, 0.15M NaCl and 0.1% PEG-8000

l  生物学信息

生物活性/药理作用

Serine protease that selectively cleaves Arg-Gly bonds in fibrinogen to form fibrin and fibrinopeptides A and B.

应 用

Thrombin is used for site specific cleavage of recombinant fusion proteins containing an accessible thrombin recognition site for removal of affinity tags. Thrombin has been used in a study to evaluate the in vitro effect of low molecular weight heparin on thrombin generation in cirrhotic patients at different stages of liver disease.

样品准备说明

Lyophilized from 0.02M Bis/Tris buffer, pH6.5, 0.15M NaCl and 0.1% PEG-8000

有效单位定义

Activity is expressed in NIH units obtained by direct comparison to a NIH Thrombin Reference Standard

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov