产品名称

Thrombin from bovine plasma

一般描述

Thrombin is the final coagulation protease in regard to hemostasis, promoting both procoagulant and anticoagulant effects.

别 称

Factor Iia

含 量

≥2,000 NIH units/mg protein (E1%/280 =19.5)

CAS  NO.

9002-04-4

MDL  number

MFCD00166053

适用范围

生物试剂

l  理化信息

外 观

冻干粉

物理形态

Lyophilized from saline sodium citrate buffer, pH6.5

l  生物学信息

生物活性/药理作用

Serine protease that selectively cleaves Arg-Gly bonds in fibrinogen to form fibrin and fibrinopeptides A and B.

应 用

Thrombin is used for site specific cleavage of recombinant fusion proteins containing an accessible thrombin recognition site for removal of affinity tags. Thrombin has been used in a study to assess a novel antiplatelet therapy in acute coronary syndromes.

样品准备说明

Lyophilized from saline sodium citrate buffer, pH6.5.Traditional thrombin products are activated with bovine brain, whereas Thrombin is activated with bovine lung and does not contain any bovine brain products.The product is soluble in water (10mg/ml), yielding a clear solution.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov