产品名称

Urokinase from human urine

含 量

≥500units/mg protein

CAS  NO.

9039-53-6

MDL  number

MFCD00132566

适用范围

生物试剂

l  理化信息

外 观

冻干粉

物理形态

Lyophilized from 1mL of 50mM Tris-HCl, pH7.4 with 100mM NaCl, 0.1% PEG 6000, and 200mM mannitol

l  生物学信息

生物活性/药理作用

Urokinase and invasiveness suppression by urinary trypsin inhibitor acts through MEK/ERK/c-Jun-dependent signaling pathways.

应 用

A complex between plasmin and an inhibitor has been isolated in a study via affinity chromatography from urokinase-activated human plasma. It has also been used in a study to investigate activation of human epithelial sodium channel (ENaC) by plasmin and chymotrypsin.

样品准备说明

Lyophilized from 1mL of 50mM Tris-HCl, pH7.4 with 100mM NaCl, 0.1% PEG 6000,and 200mM mannitol

有效单位定义

One unit will activate that amount of plasminogen which will produce a ΔA²⁷⁵ of 1.0 per ml per minute at pH7.5 at 37°C, when measuring perchloric acid soluble products from α-casein (1cm light path).

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov