产品名称

Factor V Activating Enzyme from Russell's viper venom

含 量

20units/mg protein

CAS  NO.

65522-14-7

MDL  number

MFCD00166484

适用范围

生物试剂

l  理化信息

外 观

冻干粉

物理形态

Stabilized in albumin and sodium chloride.

l  生物学信息

生物活性/药理作用

Factor V activator for RVV contains fucose, mannose, galactose, glucosamine, and neuraminic acid. Factor V activating enzyme from RVV is an arginine esterase that is sensitive to diisopropyl fluorophosphate (DFP) .

应 用

Factor V activating enzyme from Russell’s viper venom (RVV) is a single-chain glycoprotein that is involved in the rapid clotting of blood. Factor V circulates in the blood as an inactive cofactor and must be activated by proteases such as Factor V activating enzyme from RVV . This product may be useful in studying the blood coagulation cascade as well as the inherited deficiency called parahemophilia  .

样品准备说明

Stabilized in albumin and sodium chloride.

有效单位定义

One unit will increase the Factor V activity  in 0.1mL of fresh normal human plasma by at least 2× after incubation for 3 min at 37°C.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov