产品名称

HIV Protease Mutant

一般描述

recombinant, expressed in E. coli

别 称

(L33F, M46L, I54V, V82A, L90M, L10I, M36I, A71V, L63P)

分子量

mol wt ~10.8 kDa

适用范围

生物试剂

l  理化信息

物理形态

Supplied as a solution in 0.5M Sodium  Acetate, pH4.7with 50mM Tris-HCL,1M NaCL,1mM EDTA, 5mM DTT and 15% glycerol.

l  生物学信息

样品准备说明

Supplied as a solution in 0.5M Sodium Acetate, pH4.7with 50mM Tris-HCL, 1M NaCL, 1mM EDTA, 5mM DTT and 15% glycerol. Bioengineered to resist autoproteolysis, resulting in an enzyme with improved stability and substantially higher activity levels over extended time periods to conduct kinetic assays. The enzyme includes the most commonly occurring background polymorphism (L63P) that aids in the drug resistance profile.

有效单位定义

One unit of HIV protease will cleave 1picomole per minute of the substrate Abz-Ala-Arg-Val-Nle-Tyr(NO²)-Glu-Ala-Nle-NH² at 37°C.

l  存储

存储温度

−70°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov