Cathepsin D from bovine spleen
商品编号：
S0700
备注：
国外库存，货期2-4周，具体详情请联系销售人员。
详细介绍
l 基本信息 |
产品名称 | Cathepsin D from bovine spleen |
含 量 | ≥2.0units/mg protein | CAS
NO. | 9025-26-7 |
分子量 | mol wt ~45 kDa | MDL
number | MFCD00130749 |
适用范围 | 生物试剂 |
l 理化信息 |
物理形态 | Lyophilized powder containing citrate buffer salts |
l 生物学信息 |
生物活性/药理作用 | Cathepsin D is an endosomal-lysosomal aspartic protease implicated in breast cancer stasis and Alzheimer’s disease. Lysosomal release of cathepsin D has been found to precede cytochrome c release and loss of membrane potential in apoptotic human foreskin fibroblasts. Cathepsin D levels in PC12 cells increase 12 to 24 hours after apoptosis is induced. |
有效单位定义 | One unit will produce an increase in A280 of 1.0 per min per mL at pH3.0 at 37°C measured as TCA-soluble products using hemoglobin as substrate (1cm light path). |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
