产品名称

Asparaginase from Escherichia coli

别 称

L-Asparagine Amidohydrolase

含 量

100-300units/mg protein (biuret); Protein, ≥60%

MDL  number

MFCD00130565

适用范围

生物试剂

l  理化信息

外 观

白色至类白色冻干粉末

l  生物学信息

生物活性/药理作用

Asparaginase may cause cell death in leukemic cells by converting the necessary L-asparagine to aspartic acid and ammonia . Asparaginase is allosterically regulated and is crucial for proper cell functioning .

应 用

Asparaginase is used in enzymatic assays and to convert asparagine to aspartic acid. Asparaginase is used to reduce the formation of acrylamide in starchy food products. It is also used as a chemotherapy agent for acute lymphoblastic leukemia. The product is from Escherichia coli and is provided as a lyophilized powder containing sodium chloride.

样品准备说明

Lyophilized powder containing sodium chloride

有效单位定义

One unit will liberate 1.0μmole of ammonia from L-asparagine per min at pH8.6 at 37°C.

l  存储

存储温度

2-8°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov