产品名称

Amidase from Pseudomonas aeruginosa

别 称

Acrylamide Amidohydrolase, Acylase

含 量

recombinant, expressed in E. coli, hydroxamate transferase ≥200units/mg protein (biuret)

CAS  NO.

9012-56-0

MDL  number

MFCD00166319

适用范围

生物试剂

l  理化信息

外 观

甘油水的缓冲溶液

l  生物学信息

生物活性/药理作用

The amidase from Pseudomonas aeruginosa isa 6 × 38-kDa enzyme that catalyzes the hydrolysis of a small range of short aliphatic amides. Each amidase monomer is formed by a globular four-layer αββα sandwich domain with an additional 81-residue long C-terminal segment.

应 用

The importance of these hydrolases in biotechnology is growing rapidly, because their potential applications span through chemical and pharmaceutical industries as well as in bioremediation. Immobilized amidase can be used efficiently for production of acrylic acid from acrylamide, thus converting a toxic ambient contaminant into widely used industrial raw material. Amidases are potential treatments for human immunodeficiency virus and malaria. They may be used to eliminate l ions in wastewater.

样品准备说明

Solution in 50% glycerol containing 7mM 2-mercaptoethanol and phosphate buffer salt

有效单位定义

One unit will convert 1.0μmole of acetamide and hydroxylamine to acetohydroxamate and ammonia per min at pH7.2  at 37°C.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov