Penicillinase from Bacillus cereus
商品编号:
S0777
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S0777-5X25KU
有货
34190
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+
备注:
国外库存,货期2-4周,具体详情请联系销售人员。
详细介绍
l 基本信息 |
产品名称 | Penicillinase from Bacillus cereus |
一般描述 | Penicillinase from Bacillus cereus has been shown to contain three distinct species when purified and examined for homogeneity by sedimentation analysis, amino-terminal analysis, and vertical acrylamide gel electrophoresis. |
别 称 | β-Lactamase I from Bacillus cereus, β-Lactamase II, Cephalosporinase, Penicillin amido-β-lactam hydrolase |
含 量 | 1,500-3,000units/mg protein (using benzylpenicillin); Protein, ~10% |
CAS
NO. | 9073-60-3 | MDL
number | MFCD00131819 |
适用范围 | 生物试剂 |
l 理化信息 |
外 观 | 白色至浅黄色或黄褐色冻干粉末 |
物理形态 | Lyophilized powder containing phosphate and citrate buffer salts |
l 生物学信息 |
生物活性/药理作用 | Penicillinase specifically catalyzes the hydrolysis of β-lactam ring of penicillin. |
应 用 | Penicillinase can be used to reduce levels of penicillin in patients with severe penicillin reactions. Used in the
production of penicillin. Penicillinase from Bacillus cereus has been used in a comparison study with penicillinase from Bacillus subtillis where the Michaelis constant, shape of the Ph/activity curve and immunological properties were shown to be significantly different. Used in the production of penicillin. |
样品准备说明 | Lyophilized powder containing phosphate and citrate buffer salts; The product is soluble (10mg/ml) in 0.1M Tris HCl, pH7.0, containing 0.1% BSA. The solution can be filtered through a 0.2mm,
low protein-binding membrane. |
有效单位定义 | One unit will hydrolyze 1.0μmole of indicated substrate per min at pH7.0 at 25°C. Sold as benzylpenicillin units. This International Unit (using benzylpenicillin as substrate) is approximately equal to 600Levy or 75 Pollock units. |
l 存储 |
存储温度 | 2-8°C |
l 注意事项及免责声明 |
本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |