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Penicillinase from Bacillus cereus

商品编号: S0777
图示 货号 库存 价格(¥) 数量
  • S0777-1KU

    有货

    689

    - +

    S0777-5KU

    有货

    2288

    - +

    S0777-10KU

    有货

    4225

    - +

    S0777-25KU

    有货

    9126

    - +

    S0777-5X25KU

    有货

    34190

    - +

备注:

国外库存,货期2-4周,具体详情请联系销售人员。

质量文档

详细介绍

l  基本信息

产品名称

Penicillinase from Bacillus cereus

一般描述

Penicillinase from Bacillus cereus has been shown to contain three distinct species when purified and examined for homogeneity by sedimentation analysis, amino-terminal analysis, and vertical acrylamide gel electrophoresis.

别 称

β-Lactamase I from Bacillus cereus, β-Lactamase II, Cephalosporinase, Penicillin amido-β-lactam hydrolase

含 量

1,500-3,000units/mg protein (using benzylpenicillin); Protein, ~10%

CAS  NO.

9073-60-3

MDL  number

MFCD00131819

适用范围

生物试剂

l  理化信息

外 观

白色至浅黄色或黄褐色冻干粉末

物理形态

Lyophilized powder containing phosphate and citrate buffer salts

l  生物学信息

生物活性/药理作用

Penicillinase specifically catalyzes the hydrolysis of β-lactam ring of penicillin.

应 用

Penicillinase can be used to reduce levels of penicillin in patients with severe penicillin reactions. Used in the  production of penicillin. Penicillinase from Bacillus cereus has been used in a comparison study with penicillinase from Bacillus subtillis where the Michaelis constant, shape of the Ph/activity curve and immunological properties were shown to be significantly different.

Used in the production of penicillin.

样品准备说明

Lyophilized powder containing phosphate and citrate buffer salts; The product is soluble (10mg/ml) in 0.1M Tris HCl, pH7.0, containing 0.1% BSA. The solution can be filtered through a 0.2mm,  low protein-binding membrane.

有效单位定义

One unit will hydrolyze 1.0μmole of indicated substrate per min at pH7.0 at 25°C. Sold as benzylpenicillin units. This International Unit (using benzylpenicillin as substrate) is approximately equal to 600Levy or 75 Pollock units.

l  存储

存储温度

2-8°C

l  注意事项及免责声明

本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov