产品名称

Adenosine Deaminase from bovine spleen

别 称

Adenosine aminohydrolase

含 量

Type IX, 150-200units/mg protein

CAS  NO.

9026-93-1

MDL  number

MFCD00081287

分子量

32.5-33 kDa

pI

4.85

适用范围

生物试剂

l  理化信息

物理形态

Suspension in 3.2M (NH⁴)²SO⁴, 0.01M potassium phosphate, pH6.0

l  生物学信息

生物活性/药理作用

Adenosine deaminase is a purine catabolic enzyme which catalyzes the deamination of adenosine and 2′-deoxyadenosine with approximately equal specificity. It is ubiquitous in mammalian tissue, and deficiency in adenosine deaminase has been associated with severe combined immunodeficiency disease.

应 用

Adenosine deaminase is useful in various molecular biology assays, such as glycerol release assays. Adenosine deaminase is a potential target for treatments of combined immunodeficiency disease.

样品准备说明

Suspension in 3.2M (NH⁴)²SO⁴,  0.01M potassium phosphate, pH6.0; The enzyme preparation may be diluted in water or

buffer to a protein concentration of 1mg/ml, producing a clear, colorless solution.

有效单位定义

One unit will deaminate 1.0μmole of adenosine to inosine per min at pH7.5 at 25°C.

l  存储

存储温度

2-8°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov