产品名称

Pyruvate Decarboxylase from baker's yeast (S. cerevisiae)

别 称

2-Oxo-acid carboxy-lyase

含 量

5.0-20.0units/mg protein (biuret)

CAS  NO.

9001-04-1

MDL  number

MFCD00132144

适用范围

生物试剂

l  理化信息

物理形态

Suspension in 3.2M (NH⁴)²SO⁴ pH6.5, stabilized with 5% glycerol, 5mM potassium phosphate,1mM magnesium acetate, 0.5mM EDTA, and 25μM cocarboxylase.

l  生物学信息

生物活性/药理作用

Pyruvate decarboxylase (PDC) is a homotetrameric enzyme that catalyses the decarboxylation of pyruvic acid to acetaldehyde and carbon dioxide in the cytoplasm. Pyruvate decarboxylase depends on cofactors thiamine pyrophosphate (TPP) and magnesium. PDC contains a β-α-β structure, yielding parallel β-sheets.

应 用

Pyruvate decarboxylase (PDC) is used to study residues involved in thiamine pyrophosphate (TPP) binding. It is used to study the regulation of fermentation pathways in plant species.

有效单位定义

One unit will convert 1.0μmole of pyruvate to acetaldehyde per min at pH6.0 at 25°C.

l  存储

存储温度

2-8°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov