产品名称

Citrate Synthase from porcine heart

别 称

Citrate condensing enzyme, Citrate oxaloacetate lyase (CoA-acetylating)

含 量

≥100units/mg protein

CAS  NO.

9027-96-7

MDL  number

MFCD00130808

适用范围

生物试剂

l  理化信息

外 观

白色至类白色硫酸铵悬浮液

物理形态

Suspension in 3.2M (NH⁴)²SO⁴ solution, pH7.0.

溶解性(25°C)

H²O: soluble 1.0mg/mL, clear

l  生物学信息

生物活性/药理作用

Citrate synthase catalyses the conversion of citrate to acetyl-CoA in the presence of coenzyme-A with the release of H²O and oxaloacetate. The enzyme has a molecular weight of 85 kDa and a pI of 6.1-6.6. It is inhibited by fluoroacetyl-CoA, palmitoyl-CoA, and citroyl-CoA.  It is also inhibited when it is acetylated by acetic anhydride or iodinated by iodine.

样品准备说明

Suspension in 3.2M (NH⁴)²SO⁴ solution, pH 7.0.Dissolves in water to form a clear solution at 1mg/mL concentration. This enzyme is soluble in water (1mg/ml), yielding a clear solution.

有效单位定义

One unit will form 1.0μmole of citrate from oxalacetate and acetyl CoA per min at pH8.0 at 37°C.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov