产品名称

Carbonic Anhydrase from bovine erythrocytes

别 称

Carbonate Dehydratase, Carbonate Hydrolyase, Carbonic Anhydrase from bovine erythrocytes

含 量

≥95%(SDS-PAGE), specific activity ≥3,500 W-A units/mg protein; ≥85% protein basis (biuret)

CAS  NO.

9001-03-0

MDL  number

MFCD00081467

适用范围

生物试剂

l  理化信息

外 观

冻干粉

溶解性(25°C)

deionized water: >10mg/mL

l  生物学信息

生物活性/药理作用

Carbonic Anhydrase is a zinc-containing enzyme that catalyzes the reversible conversion of carbon dioxide to bicarbonate. One of its main physiological roles is to maintain the acid- balance in blood and other tissues. Lack of carbonic anhydrase results in carbonic anhydrase type II deficiency syndrome, which is an autosomal recessive disease that causes osteopetrosis, renal tubular acidosis and brain calcifications.

应 用

Carbonic anhydrase, from bovine erythrocytes, is used to create carbon dioxide capture systems and to research various purification techniques. Carbonic anhydrase is also used to study acid- regulation in fish and carbonic anhydrase type II deficiency syndrome.

有效单位定义

One Wilbur-Anderson (W-A) unit will cause the pH of a 0.02M Trizma buffer to drop from 8.3 to 6.3 per min at 0°C. (One W-A unit is essentially equivalent to one Roughton-Booth unit.)

l  存储

存储温度

2-8°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov