产品名称

Aconitase from porcine heart

别 称

Aconitate hydratase, Citrate (isocitrate) hydrolyase

CAS  NO.

9024-25-3

MDL  number

MFCD00130335

适用范围

生物试剂

l  生物学信息

生物活性/药理作用

Aconitase catalyses the stereo-specific isomerization of citrate to isocitrate via cis-aconitate in the tricarboxylic acid cycle. Aconitase is inhibited by cyanide, sulfide and copper and mercury at low concentrations. It is competitively inhibited by trans-aconitate. Aconitase contains an internal Fe-S cluster which is responsible for its activity.

应 用

Aconitase may be usefull in diabetes research as well as to study structural conservation between iron-responsive element binding proteins (IRE-BP) and isomerases .

有效单位定义

One unit will convert 1.0μmole of citrate (via cis-aconitate) to isocitrate per min at pH7.4 at 25°C.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov