Glyoxalase I from Saccharomyces cerevisiae
商品编号：
S0841
备注：
国外库存，货期2-4周，具体详情请联系销售人员。
详细介绍
l 基本信息 |
产品名称 | Glyoxalase I from Saccharomyces cerevisiae |
一般描述 | Glyoxalase detoxification system consists of glyoxalase (GLO)-I and GLO-II. GLO-I is a cytosolic, 42kDa, dimeric Zn2 lloenzyme. |
别 称 | S-Lactoyl-glutathione methylglyoxal-lyase(isomerizing) |
含 量 | Grade IV,≥400units/mg protein |
CAS
NO. | 9033-12-9 | MDL
number | MFCD00131225 |
适用范围 | 生物试剂 |
l 理化信息 |
外 观 | 无色至淡褐色的清晰或微浊的缓冲甘油水溶液 |
l 生物学信息 |
生物活性/药理作用 | Glyoxalase I is universally expressed and involved in the protection against cellular damage due to cytotoxic bolites such as advanced glycation end products (AGEs). It is an integral component of the detoxification system, catalyzing the conversion of reactive, acyclic a-oxoaldehydes into the corresponding a-hydroxyacids in a glutathione-dependent manner. |
样品准备说明 | Solution in 50% glycerol, 0.4M (NH4)2SO4 and 0.002M KH2PO4 pH6.5 |
有效单位定义 | One unit will form 1.0μmole of S-lactoylglutathione from methylglyoxal and reduced glutathione per min at pH6.6 at 25°C. |
l 存储 |
存储温度 | 2-8°C |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
