产品名称

Topoisomerase II α human (Single band on  SDS-PAGE)

一般描述

Topoisomerase II α (TopoIIα) is a gene product with conserved catalytic activities and it promotes the progression of DNA damage. The α isoform is present in proliferating cells.

别 称

p170

分子量

mol wt 170 kDa

MDL  number

MFCD03458766

适用范围

生物试剂

l  理化信息

物理形态

Buffered aqueous glycerol solution, containing Trizma buffer (pH7.7).

l  生物学信息

生物活性/药理作用

Used to study DNA structure and topology.

应 用

Topoisomerase II α has been used in a study to assess aging processes in the human brain. Topoisomerase II α has also been used in a study to investigate its activity in HIV-1 replication.

有效单位定义

One unit will decatenate 0.2μg of kinetoplast DNA in 30 minutes at 37°C.

l  存储

存储温度

−70°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov