产品名称

(Z)-Guggulsterone

一般描述

(Z)-Guggulsterone is a natural product that lowers cholesterol due to its function as an antagonist ligand for the bile acid receptor.

别称

(17Z)-Pregna-4,17(20)-diene-3,16-dione, 4,17(20)-trans-Pregnadiene-3,16-dione

纯 度

≥89.0%(HPLC)

CAS NO.

39025-23-5

分子式

C²¹H²⁸O²

分子量

312.45

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

类白色至淡黄色固体

溶解性(25℃)

DMSO

~5mg/mL

l  生物学信息

生物活性/药理作用

(Z)-Guggulsterone is a natural product that lowers cholesterol due to its function as an antagonist ligand for the bile acid receptor. (Z)-Guggulsterone is a nuclear hormone receptor that regulates the tranion of several genes involved in cholesterol metabolism and plays a role in cholesterol level regulation. (Z)-Guggulsterone is also a selective farnesoid X receptor (FXR) modulator.

l  存储

存储温度

-20℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.  https://www.ncbi.nlm.nih.gov