产品名称

Ro 11-1464

一般描述

Ro 11-1464 induces the hepatic of apoA-1 and leads to increased levels of apoA-1 in the plasma.

别称

9-Methyl-4-phenyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine

纯 度

≥98.0%(HPLC)

CAS NO.

54123-09-0

分子式

C¹⁵H¹²N⁴S

分子量

280.35

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至米色固体

溶解性(25℃)

DMSO

≥5mg/mL

l  生物学信息

生物活性/药理作用

Ro 11-1464 induces the hepatic of apoA-1 and leads to increased levels of apoA-1 in the plasma. Treatment of human apoA-1 transgenic mice with Ro 11-1464 resulted in a three-fold increase in hapoA-1 mRNA in the liver, and a two-fold increase in plama apoA-1levels. The compound causes a significant decrease in plama lipids and enhances reverse cholesterol transport.

l  存储

存储温度

-20℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.  https://www.ncbi.nlm.nih.gov