l 基本信息 |
产品名称 | CYM-5442 |
一般描述 | CYM-5442 is a highly-selective S1P1 (Spingosine 1-Phosphate Receptor 1) agonist |
别称 | 2-(4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl amino) ethanol |
纯 度 | ≥98.0%(HPLC) | CAS NO. | 1094042-01-9 |
分子式 | C23H27N3O4 | 分子量 | 409.48 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 固体 |
溶解性(25℃) | DMSO | ≥5mg/mL |
l 生物学信息 |
生物活性/药理作用 | CYM-5442 is a highly-selective S1P1(Spingosine 1-Phosphate Receptor 1) agonist that activates S1P1-dependent pathways in vitro and to levels of full efficacy in vivo through a hydrophobic pocket, separable from the orthosteric site of S1P binding that is headgroup dependent. This is a different site from those involved in the activities of other agonists such as FTY720 and
SEW2871. |
l 存储 |
存储温度 | -20℃ |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
