Gramicidin from Bacillus aneurinolyticus (Bacillus brevis)
商品编号：
S1205
备注：
国外库存，货期2-4周，具体详情请联系销售人员。
详细介绍
l 基本信息 |
产品名称 | Gramicidin from Bacillus aneurinolyticus (Bacillus brevis)(葛米素来源于解硫胺素芽胞杆菌（短芽孢杆菌）) |
一般描述 | Linear polypeptide antibiotic complex. |
别 称 | Gramicidine; Gramicidinum |
纯 度 | Linear polypeptide antibiotic complex. A
mixture of gramicidins A, B, C, and D. | CAS NO. | 1405-97-6 |
分子式 | C99H140N20O17 | 分子量 | 1882.332 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 白色至灰白色粉末或结晶粉末 |
l 生物学信息 |
生物活性/药理作用 | Linear polypeptide antibiotic mixture of gramicidin A, B, C, and D. Gramicidin A acts as neutral carrier and helps in the establishment of ion flux across the lipid b.Gramicidin D, a channel-forming ionophore that flip-flops slowly across the membrane is a known Pgp substrate and surprisingly was found to inhibit Pgp ATPase activity. This inhibition was reversed by other Pgp substrates suggesting a common drug binding site among MDR substrate-type drugs and chemosensitizers. |
应 用 | Gramicidin from Bacillus aneurinolyticus (Bacillus brevis) has been used as a control to measure the rate of diffusion of protonated β-lactams through the lipid b in liposome swelling assay. It has also been used as an analyte for the purpose of infrared laser desorption or ionization from silicon. |
l 存储 |
存储温度 | 2-8°C |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
